| 2025-09-17 | 4586 | メドレックス | 1,302,600 | 2% | ▼ | -44,800 | UBS AG | 99 | 3,010,500 |
| 2025-09-17 | 4586 | メドレックス | 1,381,700 | 2% | ▲ | 263,300 | Nomura International plc | 99 | 3,010,500 |
| 2025-09-17 | 4586 | メドレックス | 715,564 | 1% | ▼ | -443,400 | GOLDMAN SACHS INTERNATIONAL | 99 | 3,010,500 |
| 2025-09-17 | 4586 | メドレックス | 917,140 | 2% | ▲ | 158,000 | Barclays Capital Securities Ltd | 99 | 3,010,500 |
| 2025-09-17 | 4584 | キッズバイオ | 963,100 | 2% | ▲ | 25,600 | Nomura International plc | 263 | 434,700 |
| 2025-09-17 | 4584 | キッズバイオ | 824,739 | 2% | ▲ | 5,900 | MERRILL LYNCH INTERNATIONAL | 263 | 434,700 |
| 2025-09-17 | 4583 | カイオム | 382,569 | 1% | ▼ | -42,800 | Barclays Capital Securities Ltd | 134 | 321,100 |
| 2025-09-17 | 4582 | シンバイオ | 360,100 | 1% | ▲ | 100,000 | UBS AG | 142 | 6,568,700 |
| 2025-09-17 | 4582 | シンバイオ | 1,285,227 | 3% | ▲ | 319,001 | Nomura International plc | 142 | 6,568,700 |
| 2025-09-17 | 4582 | シンバイオ | 634,699 | 1% | ▼ | -24,200 | MERRILL LYNCH INTERNATIONAL | 142 | 6,568,700 |
| 2025-09-17 | 4582 | シンバイオ | 414,731 | 1% | ▲ | 21,900 | Barclays Capital Securities Ltd | 142 | 6,568,700 |
| 2025-09-17 | 4576 | ＤＷＴＩ | 1,111,672 | 2% | ▲ | 57,300 | Barclays Capital Securities Ltd | 107 | 1,236,400 |
| 2025-09-17 | 4570 | 免疫生物研 | 48,100 | 1% | ▲ | | Nomura International plc | 470 | 14,100 |
| 2025-09-17 | 4565 | ネクセラ | 1,122,956 | 1% | ▼ | -67,100 | UBS AG | 994 | 498,600 |
| 2025-09-17 | 4564 | ＯＴＳ | 7,074,500 | 2% | ▼ | -319,500 | Nomura International plc | 26 | 14,292,100 |
| 2025-09-17 | 4563 | アンジェス | 4,016,481 | 1% | ▲ | 213,800 | Barclays Capital Securities Ltd | 90 | 4,559,700 |
| 2025-09-17 | 4549 | 栄研化 | 540,479 | 1% | ▲ | 3,945 | GOLDMAN SACHS INTERNATIONAL | 2,449 | 66,200 |
| 2025-09-17 | 4544 | ＨＵグループ | 349,243 | 1% | ▼ | -102,595 | GOLDMAN SACHS INTERNATIONAL | 3,534 | 763,200 |
| 2025-09-17 | 4538 | 扶桑薬 | 107,441 | 1% | ▲ | 9,400 | Barclays Capital Securities Ltd | 2,151 | 29,800 |
| 2025-09-17 | 4528 | 小野薬 | 4,173,366 | 1% | ▲ | 1,550,000 | Barclays Bank PLC | 1,710 | 1,802,200 |
| 2025-09-17 | 4523 | エーザイ | 4,091,182 | 1% | ▲ | 193,400 | BNP Paribas Financial Markets SNC | 5,107 | 1,246,200 |
| 2025-09-17 | 4506 | 住友ファーマ | 2,295,153 | 1% | ▼ | -107,400 | Barclays Capital Securities Ltd | 1,618 | 4,902,600 |
| 2025-09-17 | 4503 | アステラス | 12,746,871 | 1% | ▲ | 644,170 | Barclays Bank PLC | 1,655 | 6,049,400 |
| 2025-09-17 | 4502 | 武田 | 15,443,960 | 1% | ▲ | 1,197,000 | Barclays Bank PLC | 4,430 | 3,664,200 |
| 2025-09-17 | 4499 | スピー | 175,762 | 2% | ▲ | 19,069 | Nomura International plc | 2,500 | 249,400 |
| 2025-09-17 | 4499 | スピー | 56,700 | 0% | ▼ | -1,400 | MERRILL LYNCH INTERNATIONAL | 2,500 | 249,400 |
| 2025-09-17 | 4493 | サイバーセキ | 150,147 | 1% | ▼ | -6,995 | Nomura International plc | 1,773 | 98,000 |
| 2025-09-17 | 4483 | ＪＭＤＣ | 440,548 | 1% | ▼ | -16,300 | MERRILL LYNCH INTERNATIONAL | 4,750 | 502,000 |
| 2025-09-17 | 4480 | メドレー | 201,500 | 1% | ▲ | 6,100 | Qube Research & Technologies Limited | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 389,155 | 1% | ▼ | -82,416 | Nomura International plc | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 531,765 | 2% | ▼ | -2,000 | MERRILL LYNCH INTERNATIONAL | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 290,372 | 1% | ▼ | -12,800 | Citigroup Global Markets Limited | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 1,362,480 | 4% | ▲ | 28,400 | Barclays Capital Securities Ltd | 2,554 | 1,291,300 |
| 2025-09-17 | 4479 | マクアケ | 84,800 | 1% | ▲ | 11,600 | UBS AG | 1,138 | 182,800 |
| 2025-09-17 | 4479 | マクアケ | 176,625 | 1% | ▲ | 11,281 | Nomura International plc | 1,138 | 182,800 |
| 2025-09-17 | 4475 | ＨＥＮＮＧＥ | 546,102 | 2% | ▼ | -26,908 | Nomura International plc | 1,764 | 465,300 |
| 2025-09-17 | 4452 | 花王 | 3,546,650 | 1% | ▲ | 1,172,863 | Nomura International plc | 6,720 | 1,265,700 |
| 2025-09-17 | 4449 | ギフティ | 461,259 | 2% | ▲ | 8,200 | MERRILL LYNCH INTERNATIONAL | 1,220 | 235,600 |
| 2025-09-17 | 4432 | ウイングアク | 168,568 | 0% | ▼ | -39,055 | GOLDMAN SACHS INTERNATIONAL | 3,370 | 119,700 |
| 2025-09-17 | 4419 | フィナＨＤ | 459,230 | 1% | ▼ | -24,800 | GOLDMAN SACHS INTERNATIONAL | 1,237 | 283,100 |
| 2025-09-17 | 4418 | ＪＤＳＣ | 71,700 | 0% | ▼ | -9,200 | Nomura International plc | 940 | 59,900 |
| 2025-09-17 | 4393 | バンクオブイ | 21,100 | 1% | ▲ | 4,300 | UBS AG | 9,110 | 62,500 |
| 2025-09-17 | 4393 | バンクオブイ | 23,500 | 1% | ▲ | 4,000 | Nomura International plc | 9,110 | 62,500 |
| 2025-09-17 | 4385 | メルカリ | 1,092,377 | 1% | ▼ | -68,900 | UBS AG | 2,317 | 3,379,300 |
| 2025-09-17 | 4385 | メルカリ | 2,579,193 | 2% | ▼ | -147,382 | Nomura International plc | 2,317 | 3,379,300 |
| 2025-09-17 | 4385 | メルカリ | 2,041,914 | 1% | ▲ | 46,093 | MERRILL LYNCH INTERNATIONAL | 2,317 | 3,379,300 |
| 2025-09-17 | 4385 | メルカリ | 2,948,691 | 2% | ▼ | -78,100 | Barclays Capital Securities Ltd | 2,317 | 3,379,300 |
| 2025-09-17 | 4369 | トリケミカル | 236,500 | 1% | ▲ | 10,400 | Qube Research & Technologies Limited | 2,806 | 1,342,100 |
| 2025-09-17 | 4369 | トリケミカル | 936,135 | 3% | ▲ | 86,200 | MERRILL LYNCH INTERNATIONAL | 2,806 | 1,342,100 |
| 2025-09-17 | 4368 | 扶桑化学 | 391,618 | 1% | ▲ | 25,245 | GOLDMAN SACHS INTERNATIONAL | 4,775 | 73,700 |
| 2025-09-17 | 4316 | ビーマップ | 121,023 | 3% | ▼ | -23,933 | Nomura International plc | 1,203 | 117,300 |
| 2025-09-17 | 4316 | ビーマップ | 19,100 | 1% | ▼ | -1,500 | Jump Trading Pacific Pte Ltd | 1,203 | 117,300 |
| 2025-09-17 | 4316 | ビーマップ | 69,843 | 2% | ▲ | 4,296 | GOLDMAN SACHS INTERNATIONAL | 1,203 | 117,300 |
| 2025-09-17 | 4316 | ビーマップ | 26,720 | 1% | ▲ | 2,300 | Barclays Capital Securities Ltd | 1,203 | 117,300 |
| 2025-09-17 | 4310 | ドリームＩ | 114,500 | 1% | ▲ | 100 | Barclays Capital Securities Ltd | 2,640 | 25,300 |
| 2025-09-17 | 4275 | カーリット | 210,824 | 1% | ▲ | 8,100 | MERRILL LYNCH INTERNATIONAL | 1,339 | 106,300 |
| 2025-09-17 | 4265 | ＩＧＳ | 72,200 | 2% | ▲ | 7,000 | UBS AG | 491 | 4,048,100 |
| 2025-09-17 | 4265 | ＩＧＳ | 35,552 | 1% | ▲ | | JANE STREET GLOBAL TRADING, LLC | 491 | 4,048,100 |
| 2025-09-17 | 4263 | サスメド | 80,300 | 0% | ▼ | -10,400 | Nomura International plc | 890 | 135,600 |
| 2025-09-17 | 4263 | サスメド | 123,100 | 1% | ▲ | 19,400 | GOLDMAN SACHS INTERNATIONAL | 890 | 135,600 |
| 2025-09-17 | 4263 | サスメド | 81,000 | 0% | ▼ | -3,700 | Barclays Capital Securities Ltd | 890 | 135,600 |
| 2025-09-17 | 4259 | エクサＷｉｚ | 653,139 | 1% | ▲ | | Nomura International plc | 515 | 879,600 |
| 2025-09-17 | 4208 | ＵＢＥ | 1,602,924 | 2% | ▲ | 55,800 | Barclays Capital Securities Ltd | 2,388 | 696,700 |
| 2025-09-17 | 4202 | ダイセル | 1,309,880 | 0% | ▼ | -53,100 | Barclays Capital Securities Ltd | 1,398 | 684,000 |
| 2025-09-17 | 4186 | 東応化 | 717,074 | 1% | ▼ | -51,378 | Nomura International plc | 4,786 | 623,700 |
| 2025-09-17 | 4176 | ココナラ | 160,914 | 1% | ▼ | -175,430 | Nomura International plc | 544 | 950,500 |
| 2025-09-17 | 4176 | ココナラ | 137,258 | 1% | ▼ | -16,500 | GOLDMAN SACHS INTERNATIONAL | 544 | 950,500 |
| 2025-09-17 | 4168 | ヤプリ | 112,600 | 1% | ▼ | -26,200 | Nomura International plc | 1,020 | 360,000 |
| 2025-09-17 | 4168 | ヤプリ | 151,065 | 1% | ▼ | -27,500 | GOLDMAN SACHS INTERNATIONAL | 1,020 | 360,000 |
| 2025-09-17 | 4166 | かっこ | 47,900 | 2% | ▲ | | UBS AG | 803 | 633,100 |
| 2025-09-17 | 4166 | かっこ | 41,600 | 2% | ▲ | 27,300 | Nomura International plc | 803 | 633,100 |
| 2025-09-17 | 4166 | かっこ | 27,400 | 1% | ▲ | | MERRILL LYNCH INTERNATIONAL | 803 | 633,100 |
| 2025-09-17 | 4166 | かっこ | 29,400 | 1% | ▲ | 3,900 | GOLDMAN SACHS INTERNATIONAL | 803 | 633,100 |
| 2025-09-17 | 4165 | プレイド | 312,762 | 1% | ▼ | -23,100 | Barclays Capital Securities Ltd | 1,085 | 351,400 |
| 2025-09-17 | 4073 | ジィ・シィ | 14,700 | 1% | ▼ | -2,500 | UBS AG | 632 | 9,100 |
| 2025-09-17 | 4072 | 電算システム | 149,154 | 1% | ▲ | 39,900 | UBS AG | 3,510 | 888,600 |
| 2025-09-17 | 4072 | 電算システム | 85,008 | 1% | ▲ | 29,754 | Nomura International plc | 3,510 | 888,600 |
| 2025-09-17 | 4072 | 電算システム | 60,114 | 1% | ▲ | | GOLDMAN SACHS INTERNATIONAL | 3,510 | 888,600 |
| 2025-09-17 | 4072 | 電算システム | 213,848 | 2% | ▲ | 25,900 | Barclays Capital Securities Ltd | 3,510 | 888,600 |
| 2025-09-17 | 4061 | デンカ | 1,771,077 | 2% | ▼ | -3,100 | Barclays Capital Securities Ltd | 2,314 | 313,400 |
| 2025-09-17 | 4059 | まぐまぐ | 15,300 | 1% | ▲ | | UBS AG | 645 | 38,600 |
| 2025-09-17 | 4051 | ＧＭＯ－ＦＧ | 38,307 | 0% | ▼ | -3,900 | GOLDMAN SACHS INTERNATIONAL | 6,240 | 29,000 |
| 2025-09-17 | 4046 | 大阪ソーダ | 913,170 | 1% | ▲ | 30,947 | MERRILL LYNCH INTERNATIONAL | 1,718 | 585,800 |
| 2025-09-17 | 4046 | 大阪ソーダ | 1,320,300 | 1% | ▼ | -39,900 | Barclays Capital Securities Ltd | 1,718 | 585,800 |
| 2025-09-17 | 4043 | トクヤマ | 945,512 | 1% | ▲ | 10,855 | GOLDMAN SACHS INTERNATIONAL | 3,687 | 342,600 |
| 2025-09-17 | 4022 | ラサ工 | 52,740 | 1% | ▼ | -6,300 | Barclays Capital Securities Ltd | 4,600 | 45,800 |
| 2025-09-17 | 4004 | レゾナック | 1,944,935 | 1% | ▲ | 335,462 | Nomura International plc | 4,635 | 1,662,400 |
| 2025-09-17 | 3994 | マネフォ | 257,498 | 0% | ▼ | -22,400 | MERRILL LYNCH INTERNATIONAL | 6,192 | 162,400 |
| 2025-09-17 | 3993 | パークシャ | 602,682 | 2% | ▲ | 50,555 | GOLDMAN SACHS INTERNATIONAL | 3,780 | 549,900 |
| 2025-09-17 | 3993 | パークシャ | 196,000 | 1% | ▲ | 28,800 | Arrowstreet Capital, Limited Partnership | 3,780 | 549,900 |
| 2025-09-17 | 3992 | ニーズウェル | 248,249 | 1% | ▲ | 11,385 | Nomura International plc | 589 | 378,100 |
| 2025-09-17 | 3962 | チェンジＨＤ | 409,611 | 1% | ▲ | 4,300 | MERRILL LYNCH INTERNATIONAL | 1,118 | 401,000 |
| 2025-09-17 | 3962 | チェンジＨＤ | 1,419,279 | 2% | ▲ | 16,240 | GOLDMAN SACHS INTERNATIONAL | 1,118 | 401,000 |
| 2025-09-17 | 3962 | チェンジＨＤ | 1,243,624 | 2% | ▲ | 85,700 | Barclays Capital Securities Ltd | 1,118 | 401,000 |
| 2025-09-17 | 3935 | エディア | 108,200 | 2% | ▲ | 6,000 | Nomura International plc | 1,191 | 289,000 |
| 2025-09-17 | 3935 | エディア | 50,297 | 1% | ▲ | 4,700 | Barclays Capital Securities Ltd | 1,191 | 289,000 |
| 2025-09-17 | 3927 | Ｆ－ブレイン | 42,534 | 1% | ▲ | 8,600 | Barclays Capital Securities Ltd | 855 | 75,800 |
| 2025-09-17 | 3915 | テラスカイ | 124,603 | 1% | ▲ | 14,300 | GOLDMAN SACHS INTERNATIONAL | 2,119 | 71,400 |
| 2025-09-17 | 3913 | ＧｒｅｅｎＢ | 23,800 | 1% | ▲ | 2,400 | BNP Paribas Financial Markets SNC | 1,078 | 77,000 |
| 2025-09-17 | 3913 | ＧｒｅｅｎＢ | 55,461 | 2% | ▲ | 2,100 | Barclays Capital Securities Ltd | 1,078 | 77,000 |