| 2025-09-17 | 4432 | ウイングアク | 168,568 | 0% | ▼ | -39,055 | GOLDMAN SACHS INTERNATIONAL | 3,370 | 119,700 |
| 2025-09-17 | 4449 | ギフティ | 461,259 | 2% | ▲ | 8,200 | MERRILL LYNCH INTERNATIONAL | 1,220 | 235,600 |
| 2025-09-17 | 4452 | 花王 | 3,546,650 | 1% | ▲ | 1,172,863 | Nomura International plc | 6,720 | 1,265,700 |
| 2025-09-17 | 4475 | ＨＥＮＮＧＥ | 546,102 | 2% | ▼ | -26,908 | Nomura International plc | 1,764 | 465,300 |
| 2025-09-17 | 4479 | マクアケ | 176,625 | 1% | ▲ | 11,281 | Nomura International plc | 1,138 | 182,800 |
| 2025-09-17 | 4479 | マクアケ | 84,800 | 1% | ▲ | 11,600 | UBS AG | 1,138 | 182,800 |
| 2025-09-17 | 4480 | メドレー | 1,362,480 | 4% | ▲ | 28,400 | Barclays Capital Securities Ltd | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 290,372 | 1% | ▼ | -12,800 | Citigroup Global Markets Limited | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 531,765 | 2% | ▼ | -2,000 | MERRILL LYNCH INTERNATIONAL | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 389,155 | 1% | ▼ | -82,416 | Nomura International plc | 2,554 | 1,291,300 |
| 2025-09-17 | 4480 | メドレー | 201,500 | 1% | ▲ | 6,100 | Qube Research & Technologies Limited | 2,554 | 1,291,300 |
| 2025-09-17 | 4483 | ＪＭＤＣ | 440,548 | 1% | ▼ | -16,300 | MERRILL LYNCH INTERNATIONAL | 4,750 | 502,000 |
| 2025-09-17 | 4493 | サイバーセキ | 150,147 | 1% | ▼ | -6,995 | Nomura International plc | 1,773 | 98,000 |
| 2025-09-17 | 4499 | スピー | 56,700 | 0% | ▼ | -1,400 | MERRILL LYNCH INTERNATIONAL | 2,500 | 249,400 |
| 2025-09-17 | 4499 | スピー | 175,762 | 2% | ▲ | 19,069 | Nomura International plc | 2,500 | 249,400 |
| 2025-09-17 | 4502 | 武田 | 15,443,960 | 1% | ▲ | 1,197,000 | Barclays Bank PLC | 4,430 | 3,664,200 |
| 2025-09-17 | 4503 | アステラス | 12,746,871 | 1% | ▲ | 644,170 | Barclays Bank PLC | 1,655 | 6,049,400 |
| 2025-09-17 | 4506 | 住友ファーマ | 2,295,153 | 1% | ▼ | -107,400 | Barclays Capital Securities Ltd | 1,618 | 4,902,600 |
| 2025-09-17 | 4523 | エーザイ | 4,091,182 | 1% | ▲ | 193,400 | BNP Paribas Financial Markets SNC | 5,107 | 1,246,200 |
| 2025-09-17 | 4528 | 小野薬 | 4,173,366 | 1% | ▲ | 1,550,000 | Barclays Bank PLC | 1,710 | 1,802,200 |
| 2025-09-17 | 4538 | 扶桑薬 | 107,441 | 1% | ▲ | 9,400 | Barclays Capital Securities Ltd | 2,151 | 29,800 |
| 2025-09-17 | 4544 | ＨＵグループ | 349,243 | 1% | ▼ | -102,595 | GOLDMAN SACHS INTERNATIONAL | 3,534 | 763,200 |
| 2025-09-17 | 4549 | 栄研化 | 540,479 | 1% | ▲ | 3,945 | GOLDMAN SACHS INTERNATIONAL | 2,449 | 66,200 |
| 2025-09-17 | 4563 | アンジェス | 4,016,481 | 1% | ▲ | 213,800 | Barclays Capital Securities Ltd | 90 | 4,559,700 |
| 2025-09-17 | 4564 | ＯＴＳ | 7,074,500 | 2% | ▼ | -319,500 | Nomura International plc | 26 | 14,292,100 |
| 2025-09-17 | 4565 | ネクセラ | 1,122,956 | 1% | ▼ | -67,100 | UBS AG | 994 | 498,600 |
| 2025-09-17 | 4570 | 免疫生物研 | 48,100 | 1% | ▲ | | Nomura International plc | 470 | 14,100 |
| 2025-09-17 | 4576 | ＤＷＴＩ | 1,111,672 | 2% | ▲ | 57,300 | Barclays Capital Securities Ltd | 107 | 1,236,400 |
| 2025-09-17 | 4582 | シンバイオ | 414,731 | 1% | ▲ | 21,900 | Barclays Capital Securities Ltd | 142 | 6,568,700 |
| 2025-09-17 | 4582 | シンバイオ | 634,699 | 1% | ▼ | -24,200 | MERRILL LYNCH INTERNATIONAL | 142 | 6,568,700 |
| 2025-09-17 | 4582 | シンバイオ | 1,285,227 | 3% | ▲ | 319,001 | Nomura International plc | 142 | 6,568,700 |
| 2025-09-17 | 4582 | シンバイオ | 360,100 | 1% | ▲ | 100,000 | UBS AG | 142 | 6,568,700 |
| 2025-09-17 | 4583 | カイオム | 382,569 | 1% | ▼ | -42,800 | Barclays Capital Securities Ltd | 134 | 321,100 |
| 2025-09-17 | 4584 | キッズバイオ | 824,739 | 2% | ▲ | 5,900 | MERRILL LYNCH INTERNATIONAL | 263 | 434,700 |
| 2025-09-17 | 4584 | キッズバイオ | 963,100 | 2% | ▲ | 25,600 | Nomura International plc | 263 | 434,700 |
| 2025-09-17 | 4586 | メドレックス | 917,140 | 2% | ▲ | 158,000 | Barclays Capital Securities Ltd | 99 | 3,010,500 |
| 2025-09-17 | 4586 | メドレックス | 715,564 | 1% | ▼ | -443,400 | GOLDMAN SACHS INTERNATIONAL | 99 | 3,010,500 |
| 2025-09-17 | 4586 | メドレックス | 1,381,700 | 2% | ▲ | 263,300 | Nomura International plc | 99 | 3,010,500 |
| 2025-09-17 | 4586 | メドレックス | 1,302,600 | 2% | ▼ | -44,800 | UBS AG | 99 | 3,010,500 |
| 2025-09-17 | 4588 | オンコリス | 781,020 | 3% | ▲ | 48,400 | Barclays Capital Securities Ltd | 616 | 261,400 |
| 2025-09-17 | 4591 | リボミック | 716,144 | 1% | ▼ | -54,800 | Barclays Capital Securities Ltd | 100 | 1,186,100 |
| 2025-09-17 | 4591 | リボミック | 165,630 | 0% | ▼ | -77,700 | MERRILL LYNCH INTERNATIONAL | 100 | 1,186,100 |
| 2025-09-17 | 4591 | リボミック | 1,390,400 | 3% | ▼ | -198,000 | Nomura International plc | 100 | 1,186,100 |
| 2025-09-17 | 4591 | リボミック | 711,700 | 1% | ▼ | -8,300 | UBS AG | 100 | 1,186,100 |
| 2025-09-17 | 4592 | サンバイオ | 389,361 | 1% | ▼ | -77,000 | Barclays Capital Securities Ltd | 2,413 | 1,978,200 |
| 2025-09-17 | 4592 | サンバイオ | 606,338 | 1% | ▲ | 36,129 | GOLDMAN SACHS INTERNATIONAL | 2,413 | 1,978,200 |
| 2025-09-17 | 4592 | サンバイオ | 373,700 | 1% | ▼ | -74,330 | Nomura International plc | 2,413 | 1,978,200 |
| 2025-09-17 | 4593 | ヘリオス | 1,040,288 | 1% | ▲ | 47,800 | MERRILL LYNCH INTERNATIONAL | 584 | 2,183,600 |
| 2025-09-17 | 4594 | ブライトパス | 1,082,000 | 1% | ▼ | -138,800 | GOLDMAN SACHS INTERNATIONAL | 72 | 1,315,000 |
| 2025-09-17 | 4596 | 窪田製薬ＨＤ | 414,000 | 1% | ▼ | -12,800 | BNP Paribas Financial Markets SNC | 73 | 4,454,600 |
| 2025-09-17 | 4597 | ソレイジア | 4,878,671 | 2% | ▼ | -934,900 | Barclays Capital Securities Ltd | 35 | 18,364,200 |
| 2025-09-17 | 4597 | ソレイジア | 1,673,200 | 1% | ▼ | -303,600 | Nomura International plc | 35 | 18,364,200 |
| 2025-09-17 | 4598 | デルタフライ | 325,073 | 3% | ▲ | 26,400 | Barclays Capital Securities Ltd | 535 | 173,300 |
| 2025-09-17 | 4598 | デルタフライ | 32,200 | 0% | ▼ | -27,000 | Nomura International plc | 535 | 173,300 |
| 2025-09-17 | 4598 | デルタフライ | 100,300 | 1% | ▼ | -13,400 | UBS AG | 535 | 173,300 |
| 2025-09-17 | 4613 | 関西ペ | 3,785,178 | 2% | ▼ | -185,212 | Nomura International plc | 2,474 | 734,700 |
| 2025-09-17 | 4613 | 関西ペ | 984,488 | 1% | ▲ | | UBS AG | 2,474 | 734,700 |
| 2025-09-17 | 4651 | サニックス | 252,200 | 1% | ▲ | 12,600 | Barclays Capital Securities Ltd | 236 | 89,400 |
| 2025-09-17 | 4666 | パーク２４ | 1,068,759 | 1% | ▲ | 150,200 | Barclays Capital Securities Ltd | 2,037 | 2,926,600 |
| 2025-09-17 | 4666 | パーク２４ | 1,218,615 | 1% | ▲ | 148,600 | MERRILL LYNCH INTERNATIONAL | 2,037 | 2,926,600 |
| 2025-09-17 | 4666 | パーク２４ | 1,352,787 | 1% | ▼ | -176,475 | Nomura International plc | 2,037 | 2,926,600 |
| 2025-09-17 | 4676 | フジＨＤ | 2,820,673 | 1% | ▲ | 160,354 | GOLDMAN SACHS INTERNATIONAL | 3,499 | 887,300 |
| 2025-09-17 | 4686 | ジャスト | 320,073 | 0% | ▼ | -15,454 | GOLDMAN SACHS INTERNATIONAL | 4,940 | 200,500 |
| 2025-09-17 | 4704 | トレンド | 3,944,629 | 3% | ▲ | 243,000 | Barclays Capital Securities Ltd | 8,340 | 1,102,500 |
| 2025-09-17 | 4751 | サイバー | 3,076,193 | 1% | ▲ | | BNP Paribas Financial Markets SNC | 1,800 | 1,980,800 |
| 2025-09-17 | 4833 | Ｄｅｆコン | 427,800 | 1% | ▼ | -89,400 | GOLDMAN SACHS INTERNATIONAL | 224 | 2,633,900 |
| 2025-09-17 | 4839 | ＷＯＷＯＷ | 136,154 | 0% | ▼ | -23,647 | Nomura International plc | 1,433 | 534,100 |
| 2025-09-17 | 4849 | エンジャパン | 327,246 | 1% | ▼ | -2,948 | MERRILL LYNCH INTERNATIONAL | 1,728 | 71,600 |
| 2025-09-17 | 4880 | セルソース | 124,300 | 1% | ▲ | 7,200 | Barclays Capital Securities Ltd | 578 | 79,200 |
| 2025-09-17 | 4882 | ペルセウス | 121,765 | 1% | ▲ | 14,300 | Barclays Capital Securities Ltd | 351 | 189,700 |
| 2025-09-17 | 4882 | ペルセウス | 135,317 | 1% | ▲ | 7,900 | GOLDMAN SACHS INTERNATIONAL | 351 | 189,700 |
| 2025-09-17 | 4883 | モダリス | 1,793,598 | 2% | ▼ | -54,000 | Barclays Capital Securities Ltd | 81 | 710,200 |
| 2025-09-17 | 4883 | モダリス | 1,899,097 | 2% | ▼ | -99,201 | Nomura International plc | 81 | 710,200 |
| 2025-09-17 | 4884 | クリングル | 74,000 | 1% | ▲ | 4,900 | Barclays Capital Securities Ltd | 491 | 56,700 |
| 2025-09-17 | 4884 | クリングル | 40,100 | 1% | ▼ | -4,500 | UBS AG | 491 | 56,700 |
| 2025-09-17 | 4888 | ステラファ | 217,100 | 1% | ▼ | -21,600 | Nomura International plc | 352 | 102,600 |
| 2025-09-17 | 4892 | サイフューズ | 47,200 | 0% | ▼ | -6,600 | UBS AG | 602 | 42,200 |
| 2025-09-17 | 4893 | ノイル | 449,500 | 1% | ▲ | 34,400 | Nomura International plc | 185 | 187,000 |
| 2025-09-17 | 4894 | クオリプス | 57,300 | 1% | ▼ | -7,000 | BNP Paribas Financial Markets SNC | 7,190 | 178,600 |
| 2025-09-17 | 4922 | コーセー | 517,609 | 1% | ▼ | -72,600 | UBS AG | 6,021 | 211,900 |
| 2025-09-17 | 4927 | ポーラＨＤ | 1,373,612 | 1% | ▼ | -1,900 | Barclays Capital Securities Ltd | 1,316 | 233,400 |
| 2025-09-17 | 4935 | リベルタ | 80,340 | 1% | ▲ | 9,300 | Barclays Capital Securities Ltd | 2,296 | 441,600 |
| 2025-09-17 | 4935 | リベルタ | 145,000 | 2% | ▲ | 25,400 | GOLDMAN SACHS INTERNATIONAL | 2,296 | 441,600 |
| 2025-09-17 | 4935 | リベルタ | 26,100 | 0% | ▼ | -5,200 | MERRILL LYNCH INTERNATIONAL | 2,296 | 441,600 |
| 2025-09-17 | 4967 | 小林製薬 | 1,019,624 | 1% | ▲ | 13,800 | Barclays Capital Securities Ltd | 5,595 | 180,500 |
| 2025-09-17 | 4971 | メック | 144,437 | 1% | ▲ | 18,770 | GOLDMAN SACHS INTERNATIONAL | 3,285 | 133,500 |
| 2025-09-17 | 4971 | メック | 187,209 | 1% | ▲ | 8,985 | MERRILL LYNCH INTERNATIONAL | 3,285 | 133,500 |
| 2025-09-17 | 4978 | リプロセル | 1,169,565 | 1% | ▼ | -184,000 | GOLDMAN SACHS INTERNATIONAL | 209 | 3,246,600 |
| 2025-09-17 | 5134 | ＰＯＰＥＲ | 39,700 | 1% | ▲ | 3,900 | UBS AG | 1,095 | 62,400 |
| 2025-09-17 | 5136 | トリプラ | 39,200 | 1% | ▼ | -10,100 | MERRILL LYNCH INTERNATIONAL | 2,140 | 553,000 |
| 2025-09-17 | 5136 | トリプラ | 30,200 | 1% | ▼ | -19,800 | UBS AG | 2,140 | 553,000 |
| 2025-09-17 | 5142 | アキレス | 106,882 | 1% | ▲ | 15,300 | Citigroup Global Markets Limited | 1,172 | 68,700 |
| 2025-09-17 | 5216 | 倉元 | 267,800 | 1% | ▲ | 30,200 | UBS AG | 202 | 325,100 |
| 2025-09-17 | 5243 | ノート | 166,552 | 1% | ▲ | 600 | GOLDMAN SACHS INTERNATIONAL | 1,274 | 77,800 |
| 2025-09-17 | 5246 | エレメンツ | 140,443 | 1% | ▲ | | Barclays Capital Securities Ltd | 1,041 | 541,800 |
| 2025-09-17 | 5246 | エレメンツ | 308,486 | 1% | ▲ | 15,400 | MERRILL LYNCH INTERNATIONAL | 1,041 | 541,800 |
| 2025-09-17 | 5246 | エレメンツ | 355,825 | 1% | ▲ | 29,133 | Nomura International plc | 1,041 | 541,800 |
| 2025-09-17 | 5246 | エレメンツ | 246,600 | 1% | ▼ | -23,400 | Qube Research & Technologies Limited | 1,041 | 541,800 |
| 2025-09-17 | 5247 | ＢＴＭ | 25,754 | 1% | ▲ | 2,500 | Barclays Capital Securities Ltd | 895 | 26,400 |
| 2025-09-17 | 5247 | ＢＴＭ | 13,900 | 0% | ▼ | -600 | BNP Paribas Financial Markets SNC | 895 | 26,400 |